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Genes with expression level regulated by genotype (N2 vs CB4856) and age at old adults stage (214 hours at 24 centigrade). |
For model 2, authors used 100 permutations to estimate the FDR threshold. Per permutation, genotypes and ages were independently randomly distributed, keeping the among-gene structure intact. Then for each spot (23,232) on the array, model 2 was tested. The obtained P-values were used to estimate a threshold for each of the explanatory factors. Authors also used a genome-wide threshold of -log10 P-value = 2, which resembles an FDR of 0.072 and 0.060 for marker and the interaction age-marker for the developing worms and FDR of 0.050 and 0.065 for marker and age-marker for the aging worms. For the physiological age effect, authors used a log10 P-value = 8 in developing worms (0.012 FDR) and -log10 P-value = 6 (0.032 FDR). |
WBPaper00040858:eQTL_age_regulated_aging
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Genes with expression level regulated by genotype (N2 vs CB4856) at Old adults stage (214 hours at 24 centigrade). |
Authors permuted transcript values and used a genome-wide threshold of log10 P-value = 2, which resembles a false discovery rate (FDR) of 0.0136. |
WBPaper00040858:eQTL_regulated_old
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Transcripts that showed significantly increased expression in gonad cyd-1(RNAi) animals in daf-2(e1370) at late L4 stage. |
DESeq2, fold change > 2, FDR < 0.05. |
WBPaper00067493:gonad-cyd-1(RNAi)_upregulated_daf-2(e1370)
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Transcripts that showed significantly increased expression in skn-1(lax188);daf-2(e1370) comparing to in skn-1(lax188) animals |
DESeq2, fold change > 2, FDR < 0.05. |
WBPaper00067765:daf-2(e1370)_upregulated_skn-1(lax188)
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Transcripts that showed significantly increased expression in N2 comparing to in skn-1 gain of function allele lax188 animals |
DESeq2, fold change > 2, FDR < 0.05. |
WBPaper00067765:skn-1(lax188)_downregulated_N2
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Genome-wide analysis of developmental and sex-regulated gene expression profile. |
self-organizing map |
cgc4489_group_2
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Transcripts that showed significantly increased expression in nath-10(icb102) comparing to in N2 at L2 larva stage. |
Differences in gene expression were calculated using the negative binomial test in the DESeq package (FDR = 0.1). |
WBPaper00061466:nath-10(icb102)_upregulated
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Transcripts that showed significantly decreased expression after synchronized L4 staged worms were treated with 10 mM caffeine at 25C for 72 hours. |
DESeq2 |
WBPaper00067717:caffeine_downregulated
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