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Genes found to be regulated by low-copy overexpression of sir-2.1 with p < 0.014. |
N.A. |
WBPaper00026929:sir-2.1_overexpression_regulated
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Germline-enriched and sex-biased expression profile cluster F. |
hierarchical clustering |
[cgc6390]:Cluster_F
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mixed oogenesis/somatic |
Comparisons were made between genotypes by subtracting the mean log value of one ratio from another, and the significance of the difference was evaluated using Student t-test for two populations. For the fem-3(gf) versus fem-1(lf) direct comparison, authors performed the same analysis, except they used a Students t-test for one population. Author chose a combination of a twofold difference with a t value exceeding 99% confidence (P < 0.01), because these criteria allowed the inclusion of essentially all genes that had previously been identified as germline-enriched in a wt/glp-4 hermaphrodite comparison. Additionally, requiring a twofold difference reduced false positives, as the number of genes with two-fold difference and a P<0.01 only included ~100 genes more than with P < 0.001, and almost all genes showed germline expression by in situ hybridization. |
[cgc6390]:mixed_oogenesis-somatic
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Transcripts that showed signifcantly decreased expression in pabp-2(RNAi) animals comparing to in N2 animals injected with empty vector at L1 larva stage and collected at L4 larva stage. |
FDR < 0.05, fold change > 2 |
WBPaper00067368:pabp-2(RNAi)_downregulated_N2
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Transcripts that showed signifcantly increased expression in ubr-5(miy31);pabp-2(RNAi) comparing to in pabp-2(RNAi) animals. |
FDR < 0.05, fold change > 2 |
WBPaper00067368:ubr-5(miy31)_upregulated_pabp-2(RNAi)
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ncRNAs with significantly decreased expression in cep-1(gk138) than in N2 after UV irradiation, according to RNAseq. |
ncRNAs with more than 2 fold difference in expression are considered differentially expressed |
WBPaper00045380:cep-1(gk138)_downregulated_UV
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