WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00302998 Gene Name  F53G2.12
Sequence Name  ? F53G2.12 Organism  Caenorhabditis elegans
Automated Description  Predicted to be involved in iron-sulfur cluster assembly. Predicted to be located in mitochondrion. Predicted to be part of L-cysteine desulfurase complex. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 19. Is an ortholog of human LYRM4 (LYR motif containing 4). Biotype  SO:0001217
Genetic Position  II:± Length (nt)  ? 1913
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Synonyms

Value
WBGene00302998

Genomics

3 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:F53G2.12a.1 F53G2.12a.1 606   II: 2477178-2479090
Transcript:F53G2.12c.1 F53G2.12c.1 90   II: 2478675-2478764
Transcript:F53G2.12b.1 F53G2.12b.1 39   II: 2479012-2479050
 

Other

3 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F53G2.12b F53G2.12b 39   II: 2479012-2479050
CDS:F53G2.12a F53G2.12a 273   II: 2478321-2478328
CDS:F53G2.12c F53G2.12c 90   II: 2478675-2478764

5 RNAi Result

WormBase ID
WBRNAi00094760
WBRNAi00048180
WBRNAi00007353
WBRNAi00032716
WBRNAi00076468

94 Allele

Public Name
WBVar02124326
gk964317
gk963801
WBVar01546428
WBVar01546429
WBVar01546430
WBVar01546431
WBVar01546432
WBVar01546433
WBVar01546434
WBVar01546435
WBVar01546436
gk136145
gk136146
gk136147
gk136148
gk136149
WBVar02028878
WBVar01764654
WBVar01502869
WBVar01502868
WBVar01502870
WBVar00100450
WBVar00100451
WBVar00100452
WBVar00100449
WBVar00100453
WBVar00100454
WBVar00214361
WBVar00214363

1 Chromosome

WormBase ID Organism Length (nt)
II Caenorhabditis elegans 15279421  

1 Chromosome Location


Feature . Primary Identifier
Start End Strand
WBGene00302998 2477178 2479090 -1

4 Data Sets

Name URL
WormBaseAcedbConverter  
GO Annotation data set  
C. elegans genomic annotations (GFF3 Gene)  
Panther orthologue and paralogue predictions  

0 Downstream Intergenic Region

14 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Proteins interacting with NHR-49-GFP according to co-IP and LC-MS. N.A. WBPaper00064071:NHR-49_interacting
Bacteria infection: Staphylococcus aureus Transcripts that showed significantly decreased expression in animals experimentally colonised by a wild microbiota community and infected by the widespread animal pathogen, Staphylococcus aureus, comparing to animals not colonized by microbiota and not infected by pathogen. DeSeq2 (v. 1.42.0), Wald analyses testing against a null hypothesis of < |1.5|-fold change in gene expression between treatments (BenjaminiHochberg adjusted false detection rate of p <= 0.05. WBPaper00067479:Microbiota-Pathogen_vs_control_downregulated
Bacteria infection: Staphylococcus aureus Transcripts that showed significantly decreased expression in animals experimentally colonised by a wild microbiota community and infected by the widespread animal pathogen, Staphylococcus aureus, comparing to animals colonized by microbiota but not infected by pathogen. DeSeq2 (v. 1.42.0), Wald analyses testing against a null hypothesis of < |1.5|-fold change in gene expression between treatments (BenjaminiHochberg adjusted false detection rate of p <= 0.05. WBPaper00067479:Microbiota-Pathogen_vs_Microbiota_downregulated
  Transcripts that showed significantly decreased expression in N2 day 15 adults comparing to in N2 day 1 adult animals according to Illumina RNASeq. DESeq fold change > 2, FDR < 0.05. WBPaper00067499:Day15_vs_Day1_downregulated_Illumina
  Genes found to be regulated by low-copy overexpression of sir-2.1 with p < 0.014. N.A. WBPaper00026929:sir-2.1_overexpression_regulated
  Transcripts that showed significantly decreased expression in hda-2(ok1479) comparing to in N2 animals. DESeq2 (version 1.28.1), FDR < 0.01, fold change > 2. WBPaper00062159:hda-2(ok1479)_downregulated
Feeding for 4 hours after L1 arrest. Transcripts that showed significantly increased expression after 4 hours of feeding of starvation-induced arrested L1 N2 animals, comparing to animals continue to starve. DESeq2, FDR < 0.05, fold change > 2. WBPaper00067518:food_upregulated_N2
  Proteins detected in gonad from single-worm studies. N.A. WBPaper00066880:gonad_expressed
  Proteins detected in intestine from single-worm studies. N.A. WBPaper00066880:intestine_expressed
Starvation for 8 hours at mid-L4 larva stage. Transcripts that showed significantly decreased expression in efk-1(ok3609) animals starved for 8 hours on unseeded plate at mid-L4 larva stage. Differential expression analysis was performed using the quasi-likelihood F-test with the generalized linear model (GLM) approach in edgeR. Fold change > 2, FDR < 0.05. WBPaper00067829:starvation_dowmregulated_efk-1(ok3609)
Bacteria infection: Staphylococcus aureus Transcripts that showed significantly decreased expression in animals infected by the widespread animal pathogen, Staphylococcus aureus, comparing to animals not infected by pathogen. DeSeq2 (v. 1.42.0), Wald analyses testing against a null hypothesis of < |1.5|-fold change in gene expression between treatments (BenjaminiHochberg adjusted false detection rate of p <= 0.05. WBPaper00067479:Pathogen_vs_control_downregulated
Feeding for 4 hours after L1 arrest. Transcripts that showed significantly increased expression after 4 hours of feeding of starvation-induced arrested L1 rsks-1(ok1255) animals, comparing to animals continue to starve. DESeq2, FDR < 0.05, fold change > 2. WBPaper00067518:food_upregulated_rsks-1(ok1255)
  Transcripts that showed significantly decreased expression in rpl-5(cc5998) comparing to in control animals. fold change > 2, FDR < 0.05 WBPaper00067708:rpl-5(cc5998)_downregulated_transcript
  Transcripts that showed significantly decreased expression in spr-5(by101) L1 animals comparing to in N2 control. DeSeq2 (v.2.11.40.2), p < 0.05. WBPaper00060886:spr-5(by101)_downregulated

0 Expression Patterns

3 GO Annotation

Annotation Extension Qualifier
  involved_in
  part_of
  located_in

7 Homologues

Type
least diverged orthologue
least diverged orthologue
least diverged orthologue
orthologue
least diverged orthologue
least diverged orthologue
least diverged orthologue

1 Locations


Feature . Primary Identifier
Start End Strand
WBGene00302998 2477178 2479090 -1

3 Ontology Annotations

Annotation Extension Qualifier
  involved_in
  part_of
  located_in

0 Regulates Expr Cluster

1 Sequence

Length
1913

1 Sequence Ontology Term

Identifier Name Description
gene  

0 Strains

1 Upstream Intergenic Region

WormBase ID Name Sequence Name Length (nt) Chromosome Location Organism
intergenic_region_chrII_2479091..2480398   1308 II: 2479091-2480398 Caenorhabditis elegans