WormBase Gene ID
|
WBGene00283745 | Gene Name | Ppa-tph-1 |
| Sequence Name
|
PPA45376 | Organism | Pristionchus pacificus |
| Automated Description | Predicted to enable iron ion binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen. Predicted to be involved in aromatic amino acid metabolic process. Expressed in ADFL; ADFR; NSML; and NSMR. Is an ortholog of C. elegans tph-1. In C. elegans, tph-1 is involved in several processes, including determination of adult lifespan; locomotory exploration behavior; and positive regulation of transforming growth factor beta receptor signaling pathway. | Biotype | SO:0001217 |
| Genetic Position | :± |
| WormMine ID | Sequence Name | Length (nt) | Chromosome Location |
|---|---|---|---|
| Transcript:PPA45376.1 | PPA45376.1 | [unknown] |
| Remark | Reporter Gene | Primary Identifier | Pattern | Subcellular Localization |
|---|---|---|---|---|
| Expr14429 | The Ppa-tph-1p::RFP reporter construct was expressed in a subset of neurons in the head region. We performed immunostaining with anti-serotonin and anti-RFP antibodies and found that RFP is expressed in NSM and ADF neurons, but not in I1 and HSN neurons. |
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