WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00224706 Gene Name  Bma-clu-1
Sequence Name  ? Bm4445 Organism  Brugia malayi
Automated Description  Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: GSKIP domain superfamily; Clustered mitochondria protein, N-terminal; Translation initiation factor eIF3 subunit 135; Tetratricopeptide-like helical domain superfamily; CLU central domain; Mitochondrial function, CLU-N-term; CLU domain containing protein; CLU domain; Clustered mitochondria; and Tetratricopeptide repeat. Is an ortholog of C. elegans clu-1. Biotype  SO:0001217
Genetic Position  :±
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm4445.1 Bm4445.1   [unknown]
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm4445 Bm4445   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

2 Data Sets

Name URL
WormBaseAcedbConverter  
GO Annotation data set  

0 Downstream Intergenic Region

3 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_M120_vs_M30
  Transcripts that showed significantly decreased expression after 48 hours of 100nM ivermectin exposure. Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method). WBPaper00049974:ivermectin_100nM_48h_downregulated
  Transcripts that showed significantly increased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_F30_vs_L4

0 Expression Patterns

1 GO Annotation

Annotation Extension Qualifier
  involved_in

0 Homologues

0 Locations

1 Ontology Annotations

Annotation Extension Qualifier
  involved_in

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

Identifier Name Description
gene  

0 Strains

0 Upstream Intergenic Region