Ppa-mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, Ppa-mab-5 is required for specification of posterior hypodermal cell fates including P8.p, a cell that fuses with the hypodermal syncytium hyp7 in wild-type animals; in Ppa-mab-5 mutant animals, P8.p forms ectopic vulva, a fate unknown from Cel-mab-5 mutants.
Organism
Pristionchus pacificus
Automated Description
Predicted to enable DNA binding activity. Is an ortholog of C. elegans mab-5. In C. elegans, mab-5 is involved in several processes, including neuroblast migration; positive regulation of mesodermal cell fate specification; and regulation of transcription by RNA polymerase II.