Ppa-tra-1 encodes Zn2+-finger-containing proteins; during development, Ppa-tra-1 functions as a key regulator of the sex determination pathway and positively regulates all aspects of hermaphrodite somatic sexual differentiation; the sequence similarity of Ppa-TRA-1 and Cel-TRA-1 is limited to the Zn2+-finger domain.
Organism
Pristionchus pacificus
Automated Description
Is predicted to encode a protein with the following domains: Zinc finger, C2H2 type; Zinc finger C2H2-type; and Zinc finger C2H2 superfamily. Is an ortholog of C. elegans tra-1. In C. elegans, tra-1 is involved in developmental process involved in reproduction; negative regulation of transcription by RNA polymerase II; and positive regulation of neuron apoptotic process.