Is predicted to encode a protein with the following domains: NAD(P)-binding domain superfamily; NAD(P)-binding domain; and GDP-mannose 4,6 dehydratase. Is an ortholog of C. elegans bre-1 and gmd-2. In C. elegans, bre-1 is involved in GDP-L-fucose biosynthetic process; GDP-mannose metabolic process; and response to toxic substance.