WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00097023 Genotype  Pmyo-3::myo-3::GFP
Phenotype Remark  cst-1/2 RNAi knockdown in Pmyo-3::myo-3::GFP nemtaodes promoted advanced muscle deterioration, including sarcomere disorganization, bending, and fragmentation. Remark  (Figure 6G) cst-1/cst-2 RNAi (dsRNA targets both genes)
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00016038 cst-2 C24A8.4 Caenorhabditis elegans
WBGene00017472 cst-1 F14H12.4 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C24A8.4 C24A8.4 1266   X: 4333192-4333346
CDS:F14H12.4a F14H12.4a 1488   X: 4339644-4339693
CDS:F14H12.4b F14H12.4b 1494   X: 4339644-4339693

1 Laboratories

Primary Identifier
LD

2 Phenotype

Identifier Name Description
WBPhenotype:0001889 body wall muscle sarcomere morphology variant Any variation in the form, structure or composition of the repeating units of a myofibrils in a muscle cell that are composed of an array of overlapping thick and thin filaments, compared to control.
WBPhenotype:0000550 body muscle dystrophy Progressive degeneration of muscle along the body wall.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00027662

0 Strain