WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Expression Pattern :

Pattern  SAD-1::GFP fluorescence was most prominent in the nerve ring and the ventral and dorsal cords, regions of the axon where the majority of synapses are made. Little or no staining was observed in the sensory dendrites or the axonal commissures, which are devoid of synapses. Weaker fluorescence was also visible in the neuronal cell bodies excluded from the nucleus. Primary Identifier  Expr814
Remark  Both wild-type SAD-1 and this GFP fusion caused paralysis and other phenotypes when expressed at high concentrations, but at the lower concentrations examined in this experiment punc-115SAD-1::GFP did not cause locomotion defects. Subcellular Localization  Little or no staining was observed in the sensory dendrites or the axonal commissures, which are devoid of synapses. Weaker fluorescence was also visible in the neuronal cell bodies excluded from the nucleus. Fluorescence appeared as a combination of punctate and diffuse staining within the axon.
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3 Anatomy Terms

Definition Name Synonym Primary Identifier
a large process bundle that runs along the vental mid-line extending from the ventral region of the nerve ring. ventral nerve cord ventral cord WBbt:0005829
the most extensive region of neuropil in the animal, consists of a large toroidal bundle of processes. nerve ring circumpharyngeal nerve ring WBbt:0006749
a bundle of nerve processes that runs along the dorsal mid-line of the animal. dorsal nerve cord dorsal cord WBbt:0006750

2 Genes

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004719 sad-1 F15A2.6 Caenorhabditis elegans
WBGene00006839 unc-115 F09B9.2 Caenorhabditis elegans

0 Life Stages