WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00225025 Gene Name  Bma-syg-1
Sequence Name  ? Bm4764 Organism  Brugia malayi
Automated Description  Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Immunoglobulin domain; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin subtype; Immunoglobulin-like fold; Immunoglobulin-like domain superfamily; Immunoglobulin I-set domain; CD80-like C2-set immunoglobulin domain; and CD80-like, immunoglobulin C2-set. Is an ortholog of C. elegans syg-1. In C. elegans, syg-1 is involved in several processes, including actin filament bundle assembly; cell-cell adhesion; and nervous system development. Biotype  SO:0001217
Genetic Position  :±
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

4 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm4764d.1 Bm4764d.1   [unknown]
Transcript:Bm4764b.1 Bm4764b.1   [unknown]
Transcript:Bm4764c.1 Bm4764c.1   [unknown]
Transcript:Bm4764a.1 Bm4764a.1   [unknown]
 

Other

4 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm4764a Bm4764a   [unknown]
CDS:Bm4764b Bm4764b   [unknown]
CDS:Bm4764c Bm4764c   [unknown]
CDS:Bm4764d Bm4764d   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

Name URL
WormBaseAcedbConverter  

0 Downstream Intergenic Region

5 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M42_vs_M30
  Transcripts that showed significantly lower expression in L3 larva comparing to in adult. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L3_vs_Adult_Downregulated
  Transcripts that showed significantly decreased expression after 5 days of 1uM ivermectin exposure. Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method). WBPaper00049974:ivermectin_1uM_5-day_downregulated
  Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to L4 male B. malayi animals. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M30_vs_L4
  Transcripts that showed significantly increased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_F30_vs_L4

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

Identifier Name Description
gene  

0 Strains

0 Upstream Intergenic Region