WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00224947 Gene Name  Bma-eat-20
Sequence Name  ? Bm4686 Organism  Brugia malayi
Automated Description  Is affected by ivermectin based on RNA-seq studies. Is predicted to encode a protein with the following domains: Follistatin-like, N-terminal and EGF-like domain. Is an ortholog of C. elegans eat-20. Biotype  SO:0001217
Genetic Position  :±
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

2 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm4686b.1 Bm4686b.1   [unknown]
Transcript:Bm4686a.1 Bm4686a.1   [unknown]
 

Other

2 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm4686b Bm4686b   [unknown]
CDS:Bm4686a Bm4686a   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

Name URL
WormBaseAcedbConverter  

0 Downstream Intergenic Region

10 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M120_vs_F120
  Transcripts that showed significantly increased expression in male B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_M120_vs_M30
  Transcripts that showed significantly lower expression in adult comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:Adult_vs_Micro_Downregulated
  Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M42_vs_M30
  Transcripts that showed significantly decreased expression after 5 days of 1uM ivermectin exposure. Differential gene expression analysis between time points and drug concentrations was realized in edgeR (version 3.10.5) through the web interface provided by NetworkAnalyst. Significance was set as an experiment-wide false discovery rate (FDR) <0.20 (after the Benjamini-Hochberg method). WBPaper00049974:ivermectin_1uM_5-day_downregulated
  Transcripts that showed significantly decreased expression in male B. malayi 30 days after infecting gerbils, comparing to female B. malayi 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M30_vs_F30
  Transcripts that showed significantly lower expression in L4 larva comparing to in microfilariae. edgeR v3.28. FDR < 0.05, fold change > 2. WBPaper00061765:L4_vs_Micro_Downregulated
  Transcripts that showed significantly increased expression in female B. malayi 120 days after infecting gerbils, comparing to 30 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:upregulated_F120_vs_F30
  Transcripts that showed significantly decreased expression in male B. malayi 42 days after infecting gerbils, comparing to female B. malayi 42 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M42_vs_F42
  Transcripts that showed significantly decreased expression in female B. malayi 30 days after infecting gerbils, comparing to L4 female B. malayi animals. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_F30_vs_L4

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

Identifier Name Description
gene  

0 Strains

0 Upstream Intergenic Region