WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

Gene :

WormBase Gene ID  ? WBGene00227906 Gene Name  Bma-tbc-2
Sequence Name  ? Bm7645 Organism  Brugia malayi
Automated Description  Is affected by 20-hydroxyecdysone based on proteomic studies. Is predicted to encode a protein with the following domains: PH-like domain superfamily; Rab-GTPase-TBC domain superfamily; Pleckstrin homology domain; PH domain; and Rab-GTPase-TBC domain. Is an ortholog of C. elegans tbc-2. In C. elegans, tbc-2 is involved in positive regulation of early endosome to late endosome transport and regulation of presynaptic dense core granule exocytosis. Biotype  SO:0001217
Genetic Position  :±
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1 Organism

Name Taxon Id
Brugia malayi 6279

0 Synonyms

Genomics

1 Transcripts

WormMine ID Sequence Name Length (nt) Chromosome Location
Transcript:Bm7645.1 Bm7645.1   [unknown]
 

Other

1 CDSs

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Bm7645 Bm7645   [unknown]

0 RNAi Result

0 Allele

0 Chromosome

0 Chromosome Location

1 Data Sets

Name URL
WormBaseAcedbConverter  

0 Downstream Intergenic Region

2 Expression Clusters

Regulated By Treatment Description Algorithm Primary Identifier
  Transcripts that showed significantly decreased expression in male B. malayi 120 days after infecting gerbils, comparing to female B. malayi 120 days after infecting gerbils. EdgeR(v3.16.5), FDR < 0.05. WBPaper00051007:downregulated_M120_vs_F120
  Proteins that showed significantly increased expression in parasites exposed to 20-hydroxyecdysone. An empirical filter of proteins with more than two peptides identified, a P value <0.05 and a greater than two-fold change of differential expression, was applied to the data. The Bonferroni correction was applied to correct the P value for the proteins analyzed. WBPaper00049261:20-hydroxyecdysone_upregulated_protein

0 Expression Patterns

0 GO Annotation

0 Homologues

0 Locations

0 Ontology Annotations

0 Regulates Expr Cluster

0 Sequence

1 Sequence Ontology Term

Identifier Name Description
gene  

0 Strains

0 Upstream Intergenic Region