WormBase Gene ID
|
WBGene00001198 | Gene Name | egl-32 |
| Brief Description | egl-32 was initially identified in screens for mutations that result in egg-laying defects; egl-32 is characterized by a single, temperature-sensitive mutation that results in increased egg retention and a reduced rate of egg laying when compared to wild-type hermaphrodites; egl-32 mutant hermaphrodites also display a small, but statistically significant decrease in ovulation rate; egl-32 is required for normal chemosensory responses mediated by the AWC neurons, and to a lesser extent for responses to odorants sensed by the AWA neurons; genetic and phenotypic analyses suggest that egl-32 activity is required during the L4 larval stage and in sperm to promote egg laying; egl-32 defects in egg-laying and chemosensation are suppressed by mutations in daf-3 and daf-5, which encode TGF-beta pathway components. | Organism | Caenorhabditis elegans |
| Automated Description | Acts upstream of or within egg-laying behavior; sensory perception of chemical stimulus; and transforming growth factor beta receptor signaling pathway. | Genetic Position | I :3.32116 ±0.007293 |
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