WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00069871 Remark  Authors used a strain expressing a GPF-based reporter harboring a premature termination codon for their experiments. In wild type, mRNAs from this transgene are degraded by the nonsense-mediated mRNA decay (NMD) pathway, and there is no GFP expression. Animals that lack the ability to carry out the NMD pathway will express GFP.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004703 rsp-6 C33H5.12 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C33H5.12a C33H5.12a 540   IV: 7790104-7790197

0 Laboratories

0 Phenotype

1 Phenotype _ Not _ Observed

Identifier Name Description
WBPhenotype:0001538 mRNA surveillance defective Defects in the cellular machinery that targets aberrant mRNAs species (nonsense codons, splice errors, altered untranslated regions etc.) for degradation. In C. elegans, mutations in such loci often act as allele-specific non gene-specific recessive suppressors of certain allele phenotypes and cause abnormal morphogenesis of male and hermaphrodite genitalia.

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00029295

0 Strain