WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00117993 Phenotype Remark  P granules are mis-localized, smaller and dispersed after dlc-1(RNAi), however Mass spectrometric analysis shows that there is no loss of the P granule components. These results show that DLC-1 does not help regulate P granule protein levels and support the model that DLC-1 facilitates phase separation of P granule components in vivo.
Remark  Exact sequence used for RNAi not stated by authors, genomic sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001005 dlc-1 T26A5.9 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T26A5.9 T26A5.9 270   III: 6463215-6463392

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0001301 P granule abnormal Localization or structural appearance of P-granules is altered compared to control. P-granules are cytoplasmic structures associated with germ nuclei in the C. elegans gonad, and are localized exclusively to germ cells, or germ cell precursors, throughout the life cycle.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00064761

0 Strain