WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00108447 Phenotype Remark  RNAi of sek-1 protected worms against the lethal effects of rotenone. Rotenone causes mitochondrial stress as it interferes with the electron transport chain. When RNAi was preformed in a strain expressing the human LRRK2 gene (wlzIs2), animals were sensitized to the effects of rotenone (i.e. this RNAi abolishes LRRK2-mediated protection against mitochondrial stress).
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004758 sek-1 R03G5.2 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R03G5.2 R03G5.2 1011   X: 7816804-7816816

0 Laboratories

2 Phenotype

Identifier Name Description
WBPhenotype:0001282 mitochondrial metabolism variant Variations in the chemical reactions and pathways of the mitochondria compared to control.
WBPhenotype:0001379 organism toxic chemical response variant Animals exhibit variations in their response to a specific toxic chemical compared to that observed in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00035592

0 Strain