WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00109112 Genotype  mev-1(kn1)
Phenotype Remark  "Likewise to the effects caused by RNAi for factors of UPRmt, the knockdown of proteins with relevance for UPR-ER such as XBP-1 (Fig. 6A), which controls a signaling pathway to prevent ER stress, or of genes activated in blocked UPR (abu) (Fig. 6B and C) excluded quercetin from exerting a survival-enhancing activity in the presence of glucose." Remark  (Figure 6B) abu-1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000024 abu-1 AC3.3 Caenorhabditis elegans
WBGene00004098 pqn-2 AC3.4 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:AC3.3 AC3.3 1278   V: 10380426-10381649
CDS:AC3.4 AC3.4 1278   V: 10382478-10382531

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0001171 shortened life span The duration of viability in the adult phase of the life-cycle is less than that of control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00044685

0 Strain