WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00114338 Genotype  Q40::YFP
Phenotype Remark  RNAi knock-down of arc-1, the C.elegans MID1 homolog, leads to a reduction of inclusion bodies and improved motility similar to the effect of the antidiabetic drugMetformin. Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation. Authors also don't state how RNAi was delivered.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000180 arc-1 ZK1320.6 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:ZK1320.6 ZK1320.6 1620   II: 9674981-9675369

0 Laboratories

2 Phenotype

Identifier Name Description
WBPhenotype:0001405 protein aggregation variant Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.
WBPhenotype:0001936 resistant to protein aggregation induced paralysis Animals fail to respond to the aggregation of proteins that elicits a paralysis response in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00055135

0 Strain