WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00094537 Genotype  alg-1(gk214)
Phenotype Remark  RNAi of alg-2 in the alg-1(gk214) mutant background results in a depletion of mature let-7 and lin-4 miRNAs as well as an accumulation of lin-4, mir-50, and mir-90 pre-miRNAs Remark  (Figure 4B, S4B) alg-2 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000106 alg-2 T07D3.7 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T07D3.7a T07D3.7a 2733   II: 873212-873266
CDS:T07D3.7b T07D3.7b 2676   II: 874162-874262

1 Laboratories

Primary Identifier
MJS

2 Phenotype

Identifier Name Description
WBPhenotype:0001779 miRNA expression variant Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.
WBPhenotype:0002155 pre miRNA processing defective The production of mature miRNA from pre-miRNA is significantly deficient compared to controls. Deficiencies in this process can result in the accumulation of pre-miRNA species and or the absence or smaller amount of mature miRNA compared to controls.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041416

0 Strain