WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00095454 Genotype  hsp-6::GFP (mtUPR)
Phenotype Remark  RNAi of phb-2 caused a robust induction of hsp-6, a commonly used mtUPR reporter strain. No induction was observed using hsp-4 promoter or hsp-16 promoter-driven GFP, reporters of the ER and cytoplasmic UPRs respectively. Remark  Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004015 phb-2 T24H7.1 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T24H7.1 T24H7.1 885   II: 6251415-6251541

1 Laboratories

Primary Identifier
KAE

2 Phenotype

Identifier Name Description
WBPhenotype:0001236 transgene expression increased Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001719 unfolded protein response variant Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00042576

0 Strain