WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00089893 Genotype  ccIs55 [unc-54::lacZ]
Phenotype Remark  RNAi was observed to significantly reduce cytosolic protein levels in body wall muscles, as determined by reduced LacZ staining compared to controls. This affect was observed after chronic RNAi exposure (RNAi continuously for two generations), as well as after acute exposure to RNAi only during adulthood. Authors warn that this RNAi produced variable results and may in fact be a false positive for inducing protein degradation. Remark  (Figure 2) dpy-2 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001064 dpy-2 T14B4.6 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T14B4.6 T14B4.6 1143   II: 6714294-6714347

1 Laboratories

Primary Identifier
CC

1 Phenotype

Identifier Name Description
WBPhenotype:0001645 protein degradation variant Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00040284

0 Strain