WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091436 Phenotype Remark  Authors observe patches of increased plasma membrane labeling by the PH-PLCdelta::mCherry reporter in embryos at cell-cell contacts, indicative of membrane accumulation. Additionally, increased labeling was observed for transmembrane proteins HMR-1 and SAX-7. Using transmission electron microscopy, the authors observed an increase in extracellular vesicles or tubules at cell-cell contacts and at the cell surface of emrbyonic cells, often resulting in the formation of a 300 nanometer gap between cells consisting of these extracellular vesicles.
Remark  (Figure 2B, 2D, 2F, S1D, S1F) tat-5 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00009498 tat-5 F36H2.1 Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F36H2.1a F36H2.1a 3225   I: 9234678-9234866
CDS:F36H2.1d F36H2.1d 3180   I: 9234678-9234866
CDS:F36H2.1b F36H2.1b 3171   I: 9234678-9234866
CDS:F36H2.1c F36H2.1c 3216   I: 9234678-9234866

1 Laboratories

Primary Identifier
FT

3 Phenotype

Identifier Name Description
WBPhenotype:0001399 cell membrane morphology variant Any variation in the structure, form or composition of the semipermeable lipid bilayer that creates a boundary between the interior and exterior environment for cells, cellular organelles and tissues, within an organism compared to control.
WBPhenotype:0001982 cell membrane organization biogenesis variant Variations in the process(es) involved in the assembly, transport, arrangement or disassembly of cell membrane structures or components compared to control.
WBPhenotype:0001117 cell cell contacts abnormal early emb Cell-cell contacts are abnormal in the early embryo.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00040428

0 Strain