|
WBPhenotype:0001645
|
protein degradation variant
|
Variations in the chemical reactions and pathways resulting in the directed breakdown of a protein (via the destruction of its native, active configuration) compared to control. |
|
WBPhenotype:0001421
|
endocytic transport variant
|
Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control. |
|
WBPhenotype:0001425
|
receptor mediated endocytosis defective
|
Animals exhibit defects in the cell-mediated uptake of external materials via receptor activity. Receptor-mediated endocytosis ensures specificity of transport and generally occurs via clathrin-coated pits and vesicles. In C. elegans, this is often judged by the lack of yolk uptake in oocytes. |