WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085189 Genotype  rrf-3(pk1426)
Phenotype Remark  RNAi depletion of F26E4.10 apparently had no effect on expression of unspliced let-7 primary transcripts, but an increase in the SL1-let-7 product (SL1 is trans-spliced to let-7) was observed. Authors note this indicates that the trans- spliced form of let-7 is a substrate for processing by the putative Drosha homolog (F26E4.10). Little if any decrease in the accumulation of mature let-7 RNA was observed. let-7 is a miRNA.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00009163 drsh-1 F26E4.10 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F26E4.10a F26E4.10a 3261   I: 9781471-9781518
CDS:F26E4.10b F26E4.10b 3246   I: 9781471-9781509

1 Laboratories

Primary Identifier
PQ

1 Phenotype

Identifier Name Description
WBPhenotype:0001779 miRNA expression variant Variations in the biogenesis or stability of the microRNA class of molecules compared to control. In C. elegans these molecules are endogenous single-stranded regulatory molecules, 19-25 nucleotides long, with the potential to arise from hairpin, foldback, structures from their primary transcripts.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00024360

0 Strain