WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00098805 Phenotype Remark  71% of isolated C blastomeres from gsk-3(RNAi) embryos produce ectopic endoderm (no wild-type C blastomeres produce endoderm)
Remark  (Table 1A) gsk-3 RNAi. First 800 bp of gsk-3 coding region used as dsRNA sequence.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001746 gsk-3 Y18D10A.5 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y18D10A.5 Y18D10A.5 1089   I: 12819362-12819454

1 Laboratories

Primary Identifier
EU

3 Phenotype

Identifier Name Description
WBPhenotype:0000354 cell differentiation variant Variations in the processes leading to the specialization of cell. Differentiation impacts diverse cellular properties such as size, shape, polarity, gene expression and responsiveness to signals/cues.
WBPhenotype:0002185 cell fate transformation to endoderm Animals develop endodermal cells/tissue from precursor cells that do not normally produce endodermal cells/tissue.
WBPhenotype:0002494 ectopic endoderm Animals exhibit one or more endodermal cells in locations not normally found in controls.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00003645

1 Strain

WormBase ID
WBStrain00000001