WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00110021 Genotype  ccIs55 [unc-54::lacZ + sup-7(st5)]
Phenotype Remark  "Next, we performed RNAi against a set of 10 knockdowns previously shown to produce embryonic lethality [icd-1 (inhibitor of celldeath), snr-6 (small nuclear ribonucleoprotein), npp-20 (nuclear pore complex protein), vha-9 (vaculolar ATPase), nap-1 (nucleosome assembly protein), ufd-1 (ubiquitin fusion degradation), fnta-1 (farnesyltransferase), pbs-2 (proteasome b-subunit), cyb-2.1 (cyclin B), and crn-1 (cell death related nuclease)]. In each case, we found embryonic lethality as expected. When these genes were knocked down in fully developed adults, we further found both increased protein degradation and loss of mitochondrial reticular structure but no defects in the sarcomere structure." Remark  snr-6 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004919 snr-6 Y49E10.15 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y49E10.15 Y49E10.15 273   III: 12429295-12429511

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000120 protein expression reduced Any change that results in lower than normal levels of protein expression compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00046120

0 Strain