WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00065157 Genotype  pha-4(zu225)
Phenotype Remark  Enhancement of pha-4(zu225) L1 lethality and RNAi in this background causes a pharynx unattached (pun) phenotype. Remark  pha-4(zu225) is a temperature sensitive allele and 24 C is a permissive temperature. The enhancement of pha-4 lethality was shown to have some specificity as no enhancement was seen in either the hsf-1(sy441), tbx-2(ut180) or lin-26(n156) backgrounds. In addiition this RNAi did not enhance the movement defect in the unc-54(r293ts) allele. Like pha-4(zu225), RNA derived from unc-54(r293) is subject to degradation by the nonsense-mediated decay pathway.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

4 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00007027 ssl-1 Y111B2A.22 Caenorhabditis elegans
WBGene00013740 hut-1 Y111B2A.20 Caenorhabditis elegans
WBGene00220229 Y111B2A.35 Y111B2A.35 Caenorhabditis elegans
WBGene00220230 Y111B2A.36 Y111B2A.36 Caenorhabditis elegans

5 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y111B2A.20a Y111B2A.20a 1023   III: 12711560-12711693
CDS:Y111B2A.22d Y111B2A.22d 6750   III: 12715723-12715899
CDS:Y111B2A.20b Y111B2A.20b 141   III: 12713527-12713667
CDS:Y111B2A.22a Y111B2A.22a 7188   III: 12714588-12714868
CDS:Y111B2A.22b Y111B2A.22b 5649   III: 12714588-12714868

1 Laboratories

Primary Identifier
SM

2 Phenotype

Identifier Name Description
WBPhenotype:0001748 pharynx unattached The pharynx or pharyngeal muscle does not form a functional connection to the mouth or buccal cavity.
WBPhenotype:0000062 lethal Animals die prematurely at any stage of the life cycle.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00028549

0 Strain