WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00112259 Genotype  rrf-3(pk1426)
Phenotype Remark  Supplementary Table 4. RNAi knockdown of cnc-2 in rrf-3(pk1426) C. elegans increases lifespan by 9% in first trial and 13% in second trial compared to rrf-3(pk1426) treated with L4440 control. In microarray, cnc-2 is downregulated in long-lived daf-2(-) in a SKN-1-dependent manner. Remark  (Supplementary Table 4) cnc-2 (WBGene00000556) RNAi. Authors state RNAi clones obtained from the Ahringer and Vidal laboratories, Ahringer clone used for curation. If Ahringer clone not available, Vidal laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000556 cnc-2 R09B5.3 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R09B5.3a R09B5.3a 219   V: 1449791-1449948
CDS:R09B5.3b R09B5.3b 189   V: 1449791-1449918

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000061 extended life span The duration of viability in the adult phase of the life-cycle surpasses that of control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00046170

0 Strain