WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00077255 Phenotype Remark  A GFP fusion with VPS-37 remained cytoplasmic in embryos co-depleted of TSG-101 and VPS-4, however simultaneous depletion of MVB-12 with VPS-4 failed to prevent the accumulation of GFP:VPS-37 on endosome membranes. Together, these data indicate that MVB-12 requires other ESCRT-I subunits for membrane association, but is itself dispensable for targeting of the remaining ESCRT-I subunits.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00015508 mvb-12 C06A6.3 Caenorhabditis elegans
WBGene00021334 vps-4 Y34D9A.10 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C06A6.3 C06A6.3 834   IV: 7830573-7830677
CDS:Y34D9A.10 Y34D9A.10 1293   I: 1054362-1054469

1 Laboratories

Primary Identifier
OD

1 Phenotype

Identifier Name Description
WBPhenotype:0001421 endocytic transport variant Animals exhibit variations in the directed movement of substances into, out of or mediated by the endosome, a membrane-bound organelle that trafficks material to different compartments of the cell or back to the plasma membrane for recycling compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00031035

1 Strain

WormBase ID
WBStrain00029229