WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00112260 Genotype  rrf-3(pk1426)
Phenotype Remark  Supplementary Table 4. RNAi knockdown of nhr-231 in rrf-3(pk1426) C. elegans increases lifespan by 14% compared to rrf-3(pk1426) treated with L4440 control. In microarray, nhr-231 is downregulated in long-lived daf-2(-) in a SKN-1-dependent manner. Remark  (Supplementary Table 4) nhr-231 (WBGene00012449) RNAi. Authors state RNAi clones obtained from the Ahringer and Vidal laboratories, Ahringer clone used for curation. If Ahringer clone not available, Vidal laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00008309 nhr-170 C54E10.5 Caenorhabditis elegans
WBGene00012449 nhr-231 Y17D7B.1 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:Y17D7B.1b Y17D7B.1b 1014   V: 18791064-18791188
CDS:C54E10.5 C54E10.5 1263   V: 18796106-18796484
CDS:Y17D7B.1a Y17D7B.1a 1194   V: 18791064-18791188

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000061 extended life span The duration of viability in the adult phase of the life-cycle surpasses that of control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00046170

0 Strain