WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00111046 Genotype  rhIs2[pat-3::HA::gfp] I; eri-1(mg366)
Phenotype Remark  Although RNAi against cyk-1, starting treatment on L1 larvae, results in thin body-wall muscle cells, body immobility in the middle/posterior, and protruding vulvas (Pvl) in young adults. Continued RNAi against cyk-1 in adults results in low penetrance of disruption of body-wall muscle cell contractile lattices. Simultaneous RNAi against inft-1 and/or inft-2 does not affect the penetrance of this late onset phenotype. fhod-1(tm2363) does not affect the penetrance of this late onset phenotype. Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000872 cyk-1 F11H8.4 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F11H8.4a F11H8.4a 4308   III: 7023838-7024005
CDS:F11H8.4b F11H8.4b 4314   III: 7023838-7024005

0 Laboratories

2 Phenotype

Identifier Name Description
WBPhenotype:0000926 body wall muscle morphology variant Any variation in the morphological appearance of the body wall muscle compared to control animals.
WBPhenotype:0001570 body wall muscle actin organization defective The characteristic organization of actin filaments into I-bands is disrupted. In C. elegans, actin filaments no longer appear as thin continuous longitudinal stripes along the muscle quadrants.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041258

0 Strain