WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00088922 Phenotype Remark  Nuclei from embryos treated with double RNAi against him-1 and either scc-1 or tim-1 had numerous FISH signals, indicating severe chromosome segregation defects and extensive aneuploidy.
Remark  paper remark: Exact sequence used for RNAi not stated by authors, genomic sequence of gene used for curation. Primers used were him-1 5' GCGTAATACGACTCACTATAGGGAAGGCAGAGAACAACTCGACTCAG 3' and 5' CGCAATTAACCCTCACTAAAGGGATCAGCAGAACCTCCGGACATA 3', scc-1 5' TAATACGACTCACTATAGGGATCCATGGAACGGAAATTTCCCGTATAG 3' and 5' TAATACGACTCACTATAGGGCGGCCGCTCCAGCGAATCCACTCTGGATAGGG.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001860 him-1 F28B3.7 Caenorhabditis elegans
WBGene00004737 scc-1 F10G7.4 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F10G7.4 F10G7.4 1938   II: 4698721-4698972
CDS:F28B3.7a F28B3.7a 3789   I: 4951810-4952031
CDS:F28B3.7b F28B3.7b 423   I: 4951810-4952031

1 Laboratories

Primary Identifier
TY

1 Phenotype

Identifier Name Description
WBPhenotype:0000773 chromosome segregation variant Any variation in the processes that regulate the apportionment of chromosomes to each of two daughter cells compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00005919

0 Strain