WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00114534 Genotype  daf-28(sa191); zcIs4 [phsp-4::GFP]
Phenotype Remark  Quote from paper: "To determine whether the developmental induction of hsp-4 is dependent on BLMP-1 function, we down-regulated blmp-1 in sa191;phsp-4::GFP animals by RNAi. Under normal growth conditions, sa191 animals that do initiate the dauer program enter the L2d stage by 41 hours postgastrula. We found no effect of blmp-1 RNAi on this initial phsp-4::GFP reporter induction at 41 hours postgastrula in all animals that had L2d morphology (Fig 3A, top row). However, by 42 hours, blmp-1 RNAi caused increased reporter fluorescence in seam cells of these animals, and by 46-47 hours, approximately half of blmp-1 RNAi animals (n= 81) exhibited induction of the reporter in the lateral hypodermis (Fig 3A and 3B)." Remark  blmp-1 (WBGene00003847) RNAi.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003847 blmp-1 F25D7.3 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F25D7.3b F25D7.3b 2406   I: 10409359-10409536
CDS:F25D7.3a F25D7.3a 2454   I: 10409359-10409536

0 Laboratories

3 Phenotype

Identifier Name Description
WBPhenotype:0001236 transgene expression increased Any increase in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001719 unfolded protein response variant Animals exhibit variations in any of the series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) and or the mitochondria, compared to control. One such response is the increase in expression of chaperones.
WBPhenotype:0001485 ER stress response variant Animals exhibit variations in their response to the presence of unfolded proteins in the endoplasmic reticulum (ER) or to other ER-related stressors compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00056441

0 Strain