WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00108790 Genotype  dvIs70 [hsp-16.2::GFP]
Phenotype Remark  "To assess whether the reduced abundance of free amino acids alters protein synthesis, we quantified the synthesis of GFP controlled by the hsp-16.2 promoter. Cycloheximide, as an inhibitor of protein synthesis, diminished the apparent GFP synthesis rate by ~30%. When pept-1 was downregulated by RNAi, the GFP synthesis rate was reduced to around 50% relative to that in wild-type animals (Figure 4B). These findings indicate that the reduced amino acid availability in pept-1 is associated with a significantly reduced de novo protein synthesis." Remark  (Figure 4B) pept-1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003877 pept-1 K04E7.2 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:K04E7.2 K04E7.2 2508   X: 6457033-6457075

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000120 protein expression reduced Any change that results in lower than normal levels of protein expression compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00045460

1 Strain

WormBase ID
WBStrain00005096