WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00113379 Genotype  punc-129::nlp-21-venus
Phenotype Remark  After RNAi animals displayed decreased NLP-21-derived VENUS levels in the DNC axons. NLP-21-VENUS is a fusion protein of the proneuropeptide NLP-21 with the yellow fluorescent protein VENUS. It was shown that NLP-21-VENUS is packaged into dense core vesicles (DCV), transported to axons of the dorsal nerve cord (DNC), and released into the body cavity. The assay used an integrated strain stably expressing fluorescently-labeled neuropeptide, NLP-21-VENUS, specifically in DA and DB cholinergic motoneurons. Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation (C38H2.1a).
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00008018 tbc-8 C38H2.1 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C38H2.1a C38H2.1a 2742   III: 10365066-10365220
CDS:C38H2.1b C38H2.1b 2058   III: 10368766-10368882

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000728 exocytosis variant Variations in the process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041154

0 Strain