WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091343 Phenotype Remark  lgg-1/lgg-2 RNAi prevents the autophagic degradation of sperm-derived "membranous organelles" (MOs) and mitochondria and thus results in persistence of these organelles in embryos as late as the 120-cell stage. The presence of paternal, sperm-derived mitochondria was confirmed by embryo PCR on mitochondrial DNA specific to the sperm.
Remark  (Figure 3, Text) lgg-1/lgg-2 RNAi. Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
Paste the following link
Lists
This RNAi isn't in any lists. Upload a list.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002980 lgg-1 C32D5.9 Caenorhabditis elegans
WBGene00002981 lgg-2 ZK593.6 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:ZK593.6b ZK593.6b 225   IV: 10934764-10934917
CDS:C32D5.9 C32D5.9 372   II: 6347263-6347346
CDS:ZK593.6a ZK593.6a 429   IV: 10934764-10934917

1 Laboratories

Primary Identifier
VIG

3 Phenotype

Identifier Name Description
WBPhenotype:0000117 L1 lethal Animals die at the L1 stage of the life cycle.
WBPhenotype:0001020 embryonic lethal late emb Animals die during the final stages of embryogenesis. In C. elegans, this lethality refers to death during the last (3-fold) stage of embryogenesis, which normally occurs 620-800 min after the first cleavage at 20C, the stage after elongation.
WBPhenotype:0000736 autophagy variant Animals exhibit variations in the process by which their cells digest parts of their own cytoplasm, compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00040387

0 Strain