WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00077612 Genotype  cul-4(gk434)
Phenotype Remark  The size of seam cell nuclei in cki-1(RNAi) cul-4(gk434) larvae was reduced approximately threefold relative to cul-4(gk434) larvae and the seam cell DNA level was reduced. This indicates that cki-1 RNAi depletion suppresses the rereplication phenotype of cul-4 mutants. Significantly, the cki-1(RNAi) cul-4(gk434) larvae still accumulated CDT-1 protein in seam cells indicating that CKI-1 is not required for the accumulation of CDT-1 and that CDT-1 accumulation is not sufficient to induce extensive rereplication.
Paste the following link
Lists
This RNAi isn't in any lists. Upload a list.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000516 cki-1 T05A6.1 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:T05A6.1 T05A6.1 555   II: 7811259-7811467

1 Laboratories

Primary Identifier
ET

2 Phenotype

Identifier Name Description
WBPhenotype:0000732 DNA metabolism variant Variations in any process that involves the maintenance, biosynthesis or accumulation of DNA in the organism compared to control.
WBPhenotype:0001567 nuclei enlarged Nuclei of specific cells are larger compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00028868

0 Strain