WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00086896 Phenotype Remark  91 to 100% of the embryos failed to hatch. ima-3(RNAi) embryos were significantly reduced in size. However, spindle formation seemed relative normal as judged from the presence of a metaphase plate and DIC images. Nuclei were formed in ima-3(RNAi) embryos upon cell division and grew to nearly normal size, illustrating that IMA-3 is not required for nuclear formation in early embryos.
Remark  ima-3, nt 745 to 1542 of predicted ORF was used for RNAi. Only intron-less sequences were amplified.
Paste the following link
Lists
This RNAi isn't in any lists. Upload a list.

1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00002074 ima-3 F32E10.4 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F32E10.4 F32E10.4 1545   IV: 7559791-7559899

0 Laboratories

3 Phenotype

Identifier Name Description
WBPhenotype:0000154 reduced brood size The characteristic number of offspring produced is lower compared to that of control animals.
WBPhenotype:0000062 lethal Animals die prematurely at any stage of the life cycle.
WBPhenotype:0001792 nuclei small Nuclei of specific cells are smaller compared to control animals.

1 Phenotype _ Not _ Observed

Identifier Name Description
WBPhenotype:0000759 spindle defective early emb Early embryos exhibit defects in the assembly, disassembly, arrangement, elongation or stabilization of the microtubules and associated molecules that form between opposite poles of a eukaryotic cell during a cell cycle.

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00005637

1 Strain

WormBase ID
WBStrain00000001