WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091021 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  GFP::RAB-11 recycling endosomes (REs) enrich apically, but with a different morphology or distribution than in wild type; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Effects on RAB-11-recycling endosome (RE) morphology or positioning differ from or are more prominent compared to effects on Golgi, early endosomes or late endosomes Remark  (Table S1, S3) H24G06.1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00019237 wdr-62 H24G06.1 Caenorhabditis elegans

6 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:H24G06.1a H24G06.1a 4974   V: 9444234-9444257
CDS:H24G06.1e H24G06.1e 2022   V: 9456286-9456343
CDS:H24G06.1g H24G06.1g 1785   V: 9456286-9456343
CDS:H24G06.1b H24G06.1b 4737   V: 9444234-9444257
CDS:H24G06.1d H24G06.1d 1872   V: 9455229-9455268
CDS:H24G06.1f H24G06.1f 2109   V: 9455229-9455268

1 Laboratories

Primary Identifier
MZE

3 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain