WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00090826 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; GFP::RAB-11 recycling endosome (RE) morphology appears diffuse or GFP::RAB-11 is cytosolically distributed; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; Autofluorescent lysosome-related organelles (AF/LROs) are enlarged or accumulated Remark  (Table S1) F45F2.2/his-39 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

7 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001878 his-4 T10C6.11 Caenorhabditis elegans
WBGene00001882 his-8 F45F2.12 Caenorhabditis elegans
WBGene00001894 his-20 K06C4.4 Caenorhabditis elegans
WBGene00001896 his-22 K06C4.12 Caenorhabditis elegans
WBGene00001913 his-39 F45F2.2 Caenorhabditis elegans
WBGene00001926 his-52 F07B7.4 Caenorhabditis elegans
WBGene00001928 his-54 F07B7.11 Caenorhabditis elegans

7 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F07B7.4 F07B7.4 372   V: 8850464-8850835
CDS:F07B7.11 F07B7.11 372   V: 8853006-8853377
CDS:K06C4.12 K06C4.12 372   V: 8892559-8892930
CDS:T10C6.11 T10C6.11 372   V: 16040144-16040515
CDS:F45F2.2 F45F2.2 204   V: 8536513-8536716
CDS:F45F2.12 F45F2.12 372   V: 8532715-8533086
CDS:K06C4.4 K06C4.4 372   V: 8895101-8895472

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002095 lysosome-related organelle morphology variant Any variation in the form or composition of membrane bound organelles, known as lysosome-related organelles (LROs) that, like lysosomes, have an acidic interior and generally act to digest components of the cell but are distinct in function, composition, and morphology, compared to control.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain