WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00098315 Genotype  Pced-1::2xFYVE::GFP (marker for phosphatidylinositol 3-phosphate (PtdIns(3)P) in apoptotic corpse-engulfing cells)
Phenotype Remark  rab-5 RNAi resulted in a reduced percentage of gonadal phagosomes labeled with 2xFYVE::GFP (a marker for phosphatidylinositol 3-phosphate (PtdIns(3)P)) and an accumulation of germ cell corpses Remark  (Figure 4E, S4) rab-5 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00004268 rab-5 F26H9.6 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F26H9.6 F26H9.6 627   I: 9308445-9308535

1 Laboratories

Primary Identifier
ZH

3 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001180 accumulated germline cell corpses Animals exhibit an increase in the quantity of germ line cells that have undergone programmed cell death but have not been engulfed.
WBPhenotype:0001846 phagosome maturation defective Early phagosomes fail to undergo the maturation process following the ingestion of particulate material by phagocytosis; During maturation, phagosomes acquire markers of late endosomes and lysosomes.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00040691

0 Strain