WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00085149 Genotype  meg-1(vr10); PGL-1::RFP
Phenotype Remark  meg-1(vr10) animals exposed to nos-2 RNAi and grown at 26 degrees C developed gonads devoid of germ cells; PGL-1::RFP expression, a marker of P granules, was mislocalized from the nuclear periphery and dispersed aberrantly into the cytoplasm; 57% of gonads failed to proliferate beyond the first two primordial germ cells, Z2 and Z3.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00001872 him-14 ZK1127.11 Caenorhabditis elegans
WBGene00003784 nos-2 ZK1127.1 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:ZK1127.1 ZK1127.1 780   II: 7065674-7065754
CDS:ZK1127.11 ZK1127.11 2529   II: 7065118-7065237

1 Laboratories

Primary Identifier
YL

4 Phenotype

Identifier Name Description
WBPhenotype:0000823 germline proliferation variant Nuclear divisions in the germ line are either expanded are reduced compared to control.
WBPhenotype:0000215 no germ line Animals lack all germline progenitor cells, thereby resulting in the complete absence of a germline.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001302 P granule localization defective The restricted localization of P granules to germ cells or germ cell precursors is altered compared to control.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038112

0 Strain