WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00094624 Genotype  F35E12.5::GFP
Phenotype Remark  aft-7 RNAi was able to reduce the expression of F35E12.5::GFP in animals that were exposed to RPW-24. RPW-24 was shown to increase the expression of the F35E12.5::GFP transcriptional reporter and to stimulate the host immune response. This effect was seen when animals were either grown on OP50 or infected P. aeruginosa PA14. Remark  RPW-24 is a molecule that protects C. elegans from bacterial infection by stimulating the host immune response. Addition of the small molecule RPW-24 was also shown to increase the expression of the F35E12.5::GFP transcriptional reporter. Exact sequence used for RNAi not stated by authors, spliced coding region sequence (07G2.2a) of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000223 atf-7 C07G2.2 Caenorhabditis elegans

4 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C07G2.2b C07G2.2b 1383   III: 4492306-4492416
CDS:C07G2.2c C07G2.2c 1530   III: 4492306-4492416
CDS:C07G2.2a C07G2.2a 1374   III: 4492306-4492416
CDS:C07G2.2d C07G2.2d 1122   III: 4492786-4493101

1 Laboratories

Primary Identifier
AU

1 Phenotype

Identifier Name Description
WBPhenotype:0001278 transgene expression reduced Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041211

0 Strain