WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00076560 Genotype  Punc-54::a-syn::gfp, Punc-54::tor-2
Phenotype Remark  Primary screen (adults). RNAi treatment enhanced aggregation of a-syn in worms coexpressing a-syn::GFP and TOR-2. The misfolded protein appeared over developmental time and was randomly distributed in the cytoplasm of the body-wall muscle cells.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

2 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003967 pdr-1 K08E3.7 Caenorhabditis elegans
WBGene00007025 mdt-29 K08E3.8 Caenorhabditis elegans

3 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:K08E3.7b K08E3.7b 732   III: 13771531-13771599
CDS:K08E3.7c K08E3.7c 975   III: 13771762-13771790
CDS:K08E3.7a K08E3.7a 1161   III: 13771531-13771599

1 Laboratories

Primary Identifier
UA

2 Phenotype

Identifier Name Description
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0001405 protein aggregation variant Variations that result in the accumulation of soluble/insoluble protein aggregates in a particular cell or tissue, compared to control. Protein aggregates are often formed by interactions between misfolded protein molecules and/or deficiencies in proper protein folding.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00031384

0 Strain