WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00091023 Genotype  unc-119(ed3) III; cbgIs91[pPept-1:pept-1::DsRed;unc-119(+)]; cbgIs98[pPept-1:GFP::rab-11.1;unc-119(+)]
Phenotype Remark  PEPT-1::DsRED accumulated in fuzzy or irregularly shaped structures; GFP::RAB-11 recycling endosomes (REs) enrich apically and along cell-cell contact sites, but with a different morphology or distribution than in wild type; GFP::RAB-11 recycling endosomes (REs) accumulate within the cell; accumulations can be of different size, abundance, and sub-cellular localisation; GFP::RAB-11 fluorescence intensity reduced; Effects on RAB-11-recycling endosome (RE) morphology or positioning differ from or are more prominent compared to effects on Golgi, early endosomes or late endosomes Remark  (Table S1, S3, Figure 3f) H39E23.1/par-1 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003916 par-1 H39E23.1 Caenorhabditis elegans

12 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:H39E23.1a H39E23.1a 3579   V: 14112802-14112915
CDS:H39E23.1b H39E23.1b 3291   V: 14112802-14112915
CDS:H39E23.1j H39E23.1j 3603   V: 14112802-14112915
CDS:H39E23.1l H39E23.1l 3321   V: 14112802-14112915
CDS:H39E23.1k H39E23.1k 1785   V: 14112802-14112915
CDS:H39E23.1g H39E23.1g 3126   V: 14112802-14112915
CDS:H39E23.1f H39E23.1f 3312   V: 14112802-14112915
CDS:H39E23.1m H39E23.1m 3390   V: 14117600-14117770
CDS:H39E23.1c H39E23.1c 3189   V: 14112802-14112915
CDS:H39E23.1d H39E23.1d 3651   V: 14112802-14112915
CDS:H39E23.1e H39E23.1e 2901   V: 14117600-14117770
CDS:H39E23.1h H39E23.1h 2118   V: 14112802-14112915

1 Laboratories

Primary Identifier
MZE

4 Phenotype

Identifier Name Description
WBPhenotype:0001278 transgene expression reduced Any decrease in the intensity of expression of a gene product produced by exogenous DNA that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0000679 transgene subcellular localization variant Any variation in the subcellular localization of a gene product produced by DNA coded for by exogenous genetic material that has been introduced into the organism compared to its expression in control animals.
WBPhenotype:0002094 RAB-11 recycling endosome morphology variant Any variation in the form or composition of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.
WBPhenotype:0002107 RAB-11 recycling endosome localization variant Any variation in the subcellular localization of membrane bound organelles, known as recycling endosomes, positive for the RAB protein RAB-11, that traffic material from early endosomes back to the plasma membrane of the cell, thereby recycling recently endocytosed material to be reused at the plasma membrane.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041129

0 Strain