WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00108068 Genotype  daf-7(e1372)
Phenotype Remark  "We next examined a TGF-b pathway that also regulates dauer formation [19-21] using genetic epistasis analyses with mutants of this pathway. In these assays, TGF-b pathway mutants were maintained on vector RNAi, pdp-1 RNAi and daf-3 RNAi (as a positive control; Table 2 and Figure S10). We first tested daf-7 mutants, which contain a mutation in the gene encoding the TGFb ligand [53]. Dauer formation of daf-7(e1372) mutants was suppressed on pdp-1 RNAi similar to daf-3 RNAi, suggesting that pdp-1 does not function at the level of daf-7 (Table 2 and Figure S10)." Remark  (Table 2,3 and Figure S10) daf-3 RNAi. Exact sequence used for RNAi not stated by authors, Ahringer laboratory clone used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000899 daf-3 F25E2.5 Caenorhabditis elegans

8 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F25E2.5a F25E2.5a 2679   X: 818320-818425
CDS:F25E2.5b F25E2.5b 2595   X: 818320-818425
CDS:F25E2.5e F25E2.5e 2586   X: 818320-818425
CDS:F25E2.5f F25E2.5f 2577   X: 818320-818425
CDS:F25E2.5g F25E2.5g 2352   X: 818320-818425
CDS:F25E2.5c F25E2.5c 2391   X: 818320-818425
CDS:F25E2.5d F25E2.5d 2688   X: 818320-818425
CDS:F25E2.5h F25E2.5h 2343   X: 818320-818425

0 Laboratories

1 Phenotype

Identifier Name Description
WBPhenotype:0000637 dauer formation variant Characteristic entry into the dauer stage is altered compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00038374

0 Strain