WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00092401 Genotype  Pdat-1::GFP; rrf-3(pk1426)
Phenotype Remark  ced-4 RNAi partially suppressed the dopaminergic neuron degeneration induced by the presence of 100 micromolar Aluminum (Al3+), implicating apoptosis in the process Remark  (Figure 6b) ced-4 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00000418 ced-4 C35D10.9 Caenorhabditis elegans

2 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:C35D10.9b C35D10.9b 1716   III: 4852325-4852775
CDS:C35D10.9a C35D10.9a 1650   III: 4852325-4852775

1 Laboratories

Primary Identifier
RJ

2 Phenotype

Identifier Name Description
WBPhenotype:0000591 metal response variant Animals exhibit variations in their response to a specific metal compared to that observed in control animals.
WBPhenotype:0000636 neuron degeneration variant Any variation in the ability of neurons to undergo a dramatic decrease in cell volume, collapse of the vacuoles and processes, and complete disintegration of the plasma membrane and most organelles under conditions that ellicit this response in control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00041701

0 Strain