WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00089666 Genotype  oxEx229 [Mos1 Substrate, Pmyo-2::GFP]; oxEx166 [hsp::MosTransposase; unc-122::gfp; lin-15(+)]
Phenotype Remark  met-2 RNAi increased the number of apoptosic bodies in gonads of animals treated with heat shock to induce Mos1 transposase-induced double stranded DNA breaks, as determined by Acridine Orange (AO) staining; met-2 RNAi also resulted in an accumulation of phosphorylated Chk1 (pChk1) protein in pachytene-stage germ lines, as determined by antibody staining Remark  (Figure 6A, 6B) met-2 RNAi
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00019883 met-2 R05D3.11 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:R05D3.11 R05D3.11 3915   III: 8375300-8375395

0 Laboratories

3 Phenotype

Identifier Name Description
WBPhenotype:0001350 protein phosphorylation increased Animals exhibit higher levels of protein phosphorylation compared to that observed in control animals.
WBPhenotype:0000183 apoptosis increased Any perturbation that causes an elevation in the frequency of cell death by apoptosis compared to control animals.
WBPhenotype:0000426 antibody staining increased Any variation that results in an increase in the characteristic expression of a gene product, as detected by antibody staining, compared to control animals.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00040176

0 Strain