WormMine

WSWS298

An integrated data resource for C. elegans and related nematodes

RNAi :

WormBase ID  WBRNAi00082044 Phenotype Remark  A short duration of RNAi feeding leads to polarity defects (symmetric two-cell embryos) while longer durations of feeding lead to unprogressed one-cell embryos. Polarity defects further shown by localization of PAR-@ and PAR-3. RNAi caused uniform PAR-3 around the cortex and PAR-2 is mislocalized to cytoplasmic foci clustered around the microtubule asters.
Remark  Exact sequence used for RNAi not stated by authors, spliced coding region sequence of gene used for curation.
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1 Organism

Name Taxon Id
Caenorhabditis elegans 6239

1 Data Sets

Name URL
WormBaseAcedbConverter  

1 Inhibits Gene

WormBase Gene ID Gene Name Sequence Name Organism
WBGene00003134 mat-3 F10C5.1 Caenorhabditis elegans

1 Inhibits Predicted Gene

WormMine ID Sequence Name Length (nt) Chromosome Location
CDS:F10C5.1 F10C5.1 2022   III: 475463-475528

1 Laboratories

Primary Identifier
HY

4 Phenotype

Identifier Name Description
WBPhenotype:0000034 embryonic polarity variant Contents or structures of an embryonic cell are not restricted/localized to the same positions (or poles) compared with control animals.
WBPhenotype:0000436 protein subcellular localization variant Any variation in the placement of a protein within in a cell or cellular compartment compared to control.
WBPhenotype:0000748 asymmetric cell division defective early emb Symmetric (PAR-like) divisions or excessive posterior displacement (zyg-8 like phenotypes).
WBPhenotype:0000040 one cell arrest early emb Embryos fail to divide and arrest as one-cell embryos.

0 Phenotype _ Not _ Observed

1 Reference

First Author Title Year Journal Volume Pages PubMed ID
            WBPaper00005095

0 Strain